The San Francisco 49ers (3-4) have lost three in a row but will have a good opportunity at breaking that streak this weekend at home against the Tennessee Titans (1-6).  The Titans are coming off their first win of the season and are a different team when Vince Young is under center.  Young, made his first start of the season last week and he and Chris Johnson led the Titans to their first win.  The 49ers need to be ready for the Titans running game, as Johnson is coming off a 228 yard performance and Young has the athleticism to use his legs and not just his arm.  Alex Smith is doing a decent job at quarterback for the 49ers though, and Titans give up 282 passing yards per game so Smith could have a big game.  He has thrown two picks in the two games he has played in, so he needs to do a better job of not turning the ball over.

The 49ers should try and wear down the Titans with the run.  They give up 112 rushing yards per game and Frank Gore is due for a big game.  He had a solid effort against the Colts last week, getting 91 yards on 13 carries including a 64 yard touchdown run.  This should be a very close match-up and the Titans seem like a different team now that they got their first win and have a new quarterback.  I think they will continue their momentum from last week, with Young and Johnson’s legs leading the way in a close win for the Titans.

FINAL SCORE PREDICTION:  Tennessee Titans 28, San Francisco 49ers 24